Chandrasekaran is SERB Distinguished Fellow at the Department of Organic Chemistry , Indian Institute of Science in Bangalore, India. He is also a Honorary Professor of the Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore. He was previously lecturer, assistant professor and professor of the Indian Institute of Technology in Kanpur, India from 1978-89. He is a synthetic organic chemist who is internationally recognized for his contributions to methodology development. His work has included the study of chemistry of Mo-S systems, organic-inorganic hybrid materials as catalysts for asymmetric synthesis, synthesis of peptides and synthesis of thiosugars as glycosidase inhibitors. He has been awarded the SS Bhatnagar Prize, CSIR, New Delhi and JC Bose National Fellowship of DST. He is a fellow of the Indian Academy of Sciences and the Indian National Science Academy.