Moncada Salvador

Professor Moncada’s scientific career began at the Royal College of Surgeons, where he was part of the team that discovered the mechanism of action of aspirin-like drugs, thus explaining how they act to relieve pain, control temperature, reduce inflammation and cause gastric damage. During his time at the Wellcome Research Laboratories he led the team that discovered thromboxane synthase and the vasodilator prostacyclin. This work is the basis for the understanding of how low doses of aspirin prevent cardiovascular cardiovascular disease and events such as heart attacks and strokes. In the 1980’s he discovered nitric oxide as a biological mediator, the mechanism of its biosynthesis and many of its biological functions. As Director of Research at Wellcome, he also presided over the work that resulted in the development of several new medicines, including Lamotrigine, Atovaquone, Somig and La